Helsinn Healthcare SA

The company's purpose is the acquisition, holding, management (administration), financing and sale of participations in other companies in Switzerland or abroad, the acquisition, sale and exploitation of technologies, know-how , patents, trademarks, licenses and products in the chemical, pharmaceutical, parapharmaceutical, veterinary and similar sectors, as well as the marketing of pharmaceutical and related products, as well as the provision of any service in this regard, both on its own behalf and on behalf of representation or commission. The Company may establish branches and subsidiaries in Switzerland and abroad, hold shares in other companies, represent third parties, as well as carry out any commercial activity and conclude any type of agreement which may be suitable for promoting the purpose of the Company, or which are directly or indirectly in relation to the same. The Company may acquire, hold, administer, encumber and sell real estate in Switzerland and abroad. Transactions prohibited by the Federal Act on the Acquisition of Funds by Persons Abroad (LAFE) are excluded. The Company, pursuing its corporate purpose, can take into account the interests of shareholders. The Company may in particular grant loans or other direct or indirect financing, including those under cash pooling agreements (including zero balancing), to directly or indirectly controlled companies and to third parties, including its direct or indirect shareholders and companies directly or indirectly controlled by them; to guarantee the obligations contracted by them, the Company may provide guarantees or securities of any kind, including lien rights on the Company's assets or fiduciary assignments of the same. All this can also happen without consideration, at preferential conditions, without interest and/or by suppressing the profit-making purpose of the Company and/or by assuming concentration risks.